Aminoacid derivatives inhibiting renin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

514 19, 530331, 530800, A61K 3700, C07K 500

Patent

active

052159671

ABSTRACT:
New amino acid derivatives of the formula

REFERENCES:
patent: 4841067 (1989-06-01), Iizuka et al.
Bolis et al., "Renin Inhibitors . . . Dipeptides Analogues . . . ", J. Med. Chem. 1987, 30, 1729-1737.
Denkewalter et al., "Progress in Drug Research", vol. 10, 1966, pp. 510-512.
Burger, "Medicinal Chemistry", 2nd Ed, 1960, pp. 565-571, 578-581, 600-601.
Haber et al., "Renin Inhibitors: A Search for Principles of Design", J. Cardiovascular Pharmacology, 10 (Suppl. 7)5:54-58, 1987.
Plattner et al., "Renin Inhibitors. Dipeptide Analogues", J. Med. Chem. 1988, 31, 2272-2288.

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