Aminoacetylmercapto derivatives useful as inhibitors of enkephal

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

540527, 540520, A61K 3135, C07D49506

Patent

active

055299954

ABSTRACT:
The present invention relates to novel aminoacetylmercapto derivatives useful as inhibitors of enkephalinase and ACE.

REFERENCES:
patent: 4973585 (1990-11-01), Flynn et al.
patent: 5238932 (1994-07-01), Flynn et al.
patent: 5424425 (1995-06-01), Flynn et al.
Flynn, et al., J. Am. Chem. Soc. 109, 7914 (1987).
Flynn, et al., Peptide Chemistry (1987); T. Shiba & Sakakibara (ed.), Protein Research Foundation, Osaka (1988).
Flynn, et al., Tetrahedron Letters, vol. 31 (6), 815-88 (1990).
Attwood, et al., J. Chem. Soc. Perkin Trans. I, pp. 1011-1019 (1986).
Natoff, et al., Drugs of the Future, vol. 12 (5): 475-483 (1987).
Journal of Am. Coll. of Card. vol 17, No. 6, pp. 137B-142B (May 1991).
Supplement I Cir. vol. 86(4) pp. 1-220 (0873) (Oct. 1992).
J. Med. Chem. 1992, 35, 823-832, Timothy D. Ocain et al.
Bioorganic and Medical Chem. Letters Vo. 1, 309, 1991.
Fournie-Zaluski, Marie-Claude et al., J. Med. Chem., 1992 vol. 35, pp. 2473-2481.
Fournie-Zaluski, Marie-Claude et al., J. Med. Chem., 1992 vol. 35, pp. 1259-1266.
French, John F., Jour. of Pharm and Exper. Therapeutics, vol. 268, No. 1, pp. 180-186.
W. H. Parsons et al. Biochemical and Biophysical Research Communications vol. 117, No. 1, 1993 (Nov. 30, 1983).
Burkholder, et al. Bioorganic and Medical Chem. Letters, vol. 3, No. 2, pp. 231-234, 1993.
Flynn et al., J. Med. Chem. 1993, 36 2420-2423.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Aminoacetylmercapto derivatives useful as inhibitors of enkephal does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aminoacetylmercapto derivatives useful as inhibitors of enkephal, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aminoacetylmercapto derivatives useful as inhibitors of enkephal will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2188948

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.