Amino substituted taxanes

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549511, C07D30514

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active

060517247

ABSTRACT:
Taxane derivatives having an amino substituted C13 side chain.

REFERENCES:
patent: 4680391 (1987-07-01), Firestone et al.
patent: 4814470 (1989-03-01), Colin et al.
patent: 4857653 (1989-08-01), Colin et al.
patent: 4876399 (1989-10-01), Holton et al.
patent: 4924011 (1990-05-01), Denis et al.
patent: 4924012 (1990-05-01), Colin et al.
patent: 4942184 (1990-07-01), Haugwitz et al.
patent: 5015744 (1991-05-01), Holton
patent: 5175315 (1992-12-01), Holton
patent: 5227400 (1993-07-01), Holton et al.
patent: 5229526 (1993-07-01), Holton
patent: 5243045 (1993-09-01), Holton et al.
patent: 5250683 (1993-10-01), Holton et al.
patent: 5264591 (1993-11-01), Bombardelli et al.
patent: 5272171 (1993-12-01), Ueda et al.
patent: 5274124 (1993-12-01), Holton
patent: 5294637 (1994-03-01), Chen et al.
patent: 5338872 (1994-08-01), Holton et al.
patent: 5352806 (1994-10-01), Gunawardana et al.
patent: 5399726 (1995-03-01), Holton et al.
patent: 5430160 (1995-07-01), Holton
patent: 5440056 (1995-08-01), Klein et al.
patent: 5466834 (1995-11-01), Holton
patent: 5478854 (1995-12-01), Farina et al.
patent: 5489601 (1996-02-01), Holton et al.
patent: 5530020 (1996-06-01), Gunawardana et al.
patent: 5539103 (1996-07-01), Holton
patent: 5594157 (1997-01-01), Gunawardana et al.
patent: 5614645 (1997-03-01), Kingston et al.
patent: 5616740 (1997-04-01), Klein et al.
Science/Technology "New Family of Taxol, Taxotere Analogs Developed", Chem. & Engineering News, pp. 26-27 (Apr. 12, 1993).
Ojima et al., "New and Efficient Approaches To The Semisynthesis of Taxol And its C-13 Side Chain Analogs By Means Of .beta.-Lactam Synthon Method", Tetrahedron vol. 48, No. 34, pp. 6985-7012 (1992).
International Search Report issued for PCT/US93/10813 dated Mar. 11, 1994.
U.S. application No. 08/372,103 filed Jan. 13, 1995.
U.S. application No. 08/483,309 filed Jun. 7, 1995.
U.S. application No. 08/026,978 filed Mar. 5, 1993.
U.S. application No. 08/351,690 filed Dec. 7, 1994.
G. Samaranayake et al. "Modified Taxols. 5.1 Reaction of Taxol with Electrophilic Reagents and Preparation of a Rearranged Taxol Derivative with Tubulin Assembly Activity." Journal of Organic Chemistry, 56:17, pp. 5114-5119 (1991).
D. Kingston et al. "Progress in the Chemistry of Organic Natural Products" Springer-Verlag, New York (1993) pp. 60, 61, 67, 112, 113, 170, 171.
V. Farina et al. "The Chemistry of Taxanes: Unexpected Rearrangement of Baccatin III During Chemoselective Debenzoylation with Bu.sub.3 SnOMe/LiCl" Tetrahedron Letters, 33:28 (1992) pp. 3979-3982.
K.C. Nicolaou et al., "Chemistry and Biology of Taxol" Angewandte Chemie (ACIEAY), vol. 33, No. 1 (Jan. 17, 1994), pp. 15-44.

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