Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-06-25
1994-02-01
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514212, 514218, 5142285, 5142332, 540575, 540600, 544 60, 544115, 544250, 544370, 544391, 544392, 544393, 546271, 546337, 5483061, 5483097, 5483101, 564 34, 564 35, 564 50, 564218, 564431, A61K 31505, C07D48704, C07D23516, C07C27540
Patent
active
052832481
ABSTRACT:
The present invention relates to novel substituted pyrimidobenzimidazole derivatives of the formula ##STR1## wherein the substituents are as described in the specification, and pharmaceutically acceptable salts thereof.
The products have an inhibitory action on the DNA-gyrase activity in bacteria. They can accordingly be used for the prevention or control of bacterial infections.
REFERENCES:
patent: 4209523 (1980-06-01), Lafon
patent: 4246196 (1981-01-01), Arndt et al.
Hubschwerlen et al., Chemical Abstracts, vol. 116, No. 6577 (1992) (Abstract for CA 2028530, May 22, 1991).
Yogo et al Chem. Pharm. Bull. 32(9) pp. 3695-3697 (1984).
Badawey et al J. Heterocyclic Chem. 26 pp. 1401-1404 Sep. Oct. 1989.
Badawey et al. J. Heterocyclic Chem. 26 pp. 405-408 (1989).
R. Otter and N. R. Cozzarelli, Methods in Enzymology, vol. 100, pp. 171-180 (1983).
Davies et al. Pyrimido (3,4-a)Benzimidazole Novel Ring System, Journal of the Chemical Society, pp. 5125-5127 (1965).
Hubschwerlen Christian
Kompis Ivan
Specklin Jean-Luc
Bernhardt Emily
Ciambrone Coletti Ellen
Gould George M.
Hoffmann-La Roche Inc.
Johnston George W.
LandOfFree
Amino substituted pyrimido[1,6-2]benzimidazoles does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Amino substituted pyrimido[1,6-2]benzimidazoles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amino substituted pyrimido[1,6-2]benzimidazoles will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-580005