Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-05-15
1997-07-01
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530331, 514 18, A61K 3805
Patent
active
056438796
ABSTRACT:
The invention concerns novel renin-inhibitory compounds which contain an amino-substituted heterocycle at the P.sub.2 position. These are useful for treating renin-associated hypertension, congestive heart failure, glaucoma, hyperaldosteronism, and diseases caused by retroviruses including HTLV-I and -III. Processes for preparing the compounds, compositions containing them, and methods of using them are included. Also included is a diagnostic method which uses the compounds to determine the presence of renin-associated hypertension, or hyperaldosteronism.
REFERENCES:
patent: 5178877 (1993-01-01), Garren et al.
patent: 5178887 (1993-01-01), Garren et al.
J. Med Chem., vol. 30, 1987 pp. 1224-1228.
Connolly Cleo
Doherty Annette Marion
Hamilton Harriet Wall
Patt William Chester
Sircar Ila
Anderson Elizabeth M.
Lukton David
Tsang Cecilia J.
Warner-Lambert & Company
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