Amino substituted aryloxybenzylpiperidine derivatives

Details Amino substituted aryloxybenzylpiperidine derivatives Amino substituted aryloxybenzylpiperidine derivatives

2005-09-20

2008-11-04

Saeed, Kamal (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S315000

Reexamination Certificate

active

07446204

ABSTRACT:
This invention is directed to Amino substituted Aryloxybenzylpiperidine derivatives which are ligands at the MCH1 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by admixing a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject a therapeutically effective amount of a compound of the subject invention. This invention also provides a method of treating a subject suffering from obesity which comprises administering to the subject a therapeutically effective amount of a compound of the subject invention.

REFERENCES:
patent: 6503928 (2003-01-01), Kelly et al.
patent: 6727264 (2004-04-01), Marzabadi et al.
patent: 7067534 (2006-06-01), Marzabadi et al.
patent: 2006/0079522 (2006-04-01), Marzabadi et al.
patent: 1 020 434 (2000-07-01), None
patent: WO 02/094799 (2002-11-01), None
patent: WO 2004/005257 (2004-01-01), None
patent: WO 2004/052848 (2004-06-01), None
Browning, “Recent developments in the discovery of melanin-concentrating hormone antagonists:novel antiobesity agents”, Expert Opinion in Therapeutic Patents, Mar. 2004, 14(3):313-325.
Carpenter & Hertzog, “Melanin-concentrating hormone receptor antagonists as potential antiobesity agents”, Expert Opinion in Therapeutic Patents, Nov. 2002, 12(11):1639-1646.
Collins & Kym, “Prospects for obesity treatment: MCH receptor antagonists”, Current Opinion in Investigational Drugs, Apr. 2003, 4(4):386-394.
Kowalski & McBriar, “Therapeutic potential of melanin-concentrating hormone-1 receptor antagonists for the treatment of obesity”, Expert Opinion in Investigational Drugs, Sep. 2004, 13(9):1113-1122.
Takekawa, et al., “T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist”, European Journal of Pharm., Mar. 2002, 438(3):129-135.

Affiliated with

Also associated with

Rating

Amino substituted aryloxybenzylpiperidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amino substituted aryloxybenzylpiperidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amino substituted aryloxybenzylpiperidine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4050868