Amino-spiro[oxa(or thia)cycloalkane-penam]-carboxylic

Details Amino-spiro[oxa(or thia)cycloalkane-penam]-carboxylic Amino-spiro[oxa(or thia)cycloalkane-penam]-carboxylic

1978-01-16

1979-01-30

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602391, 424271, C07D27704

Patent

active

041372360

ABSTRACT:
Amino-spiro[oxa(or thia)cycloalkane-penam]-carboxylic acid, a salt or an ester thereof, of the formula ##STR1## wherein Z is a hydrogen or an alkali metal atom, or a group protecting the carboxylic function, X is a sulfur or oxygen atom, n is 1 or 2, m is 1 or 2, and process of preparing the same.
These compounds are useful as intermediates in the synthesis of a new group of antibiotics having properties similar to penicillins, besides own antibiotic activity with a broad antibacterial spectrum.

REFERENCES:
patent: 3047467 (1962-07-01), Doyle et al.
patent: 3129217 (1964-04-01), Doyle et al.
patent: 3134767 (1964-05-01), Doyle et al.
patent: 3210337 (1965-10-01), Chow et al.

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