Amino pyridine derivatives

Details Amino pyridine derivatives Amino pyridine derivatives

1978-01-30

1979-12-25

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546270, 546304, 546312, C07D21338

Patent

active

041806700

ABSTRACT:
Novel 4-pyridinamine derivatives having the formula ##STR1## [where R.sup.1 and R.sup.2 are aryl or heteroaryl (optionally linked together by a lower alkylene bridge) or one of R.sup.1 and R.sup.2 is aryl or heteroaryl and the other of R.sup.1 and R.sup.2 is lower alkyl or ar(lower)alkyl, R.sup.3 and R.sup.4 are each hydrogen or lower alkyl and n is 0 or 1] and their non-toxic acid addition salts are described. They show CNS activity and may be used as antidepressant drugs. Some also show stimulant activity.
Novel intermediates having the formula ##STR2## are also described.

REFERENCES:
patent: 2974139 (1961-03-01), Schuler al.
patent: 3926611 (1975-12-01), Tomlin et al.
Carpenedo et al., Chem. Abstracts, vol. 73, p. 236, item 108,061s, (1970).

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