Amino-propranolol

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2601127, 260285, 26029354, 2603191, 2603975, 2605705C, 2605706, 424316, 424330, 548300, 560 19, C07C 9306

Patent

active

040511863

ABSTRACT:
Biologically active substances having labile aryl groups can be converted to the corresponding aryl amine derivatives. The biologically active substances are reacted with a diazonium compound which optionally can be linked to a solid, inorganic carrier such as porous glass beads for ease of purification. The diazo reaction product is then reductively cleaved with a chemical reducing agent such as with hydrosulfite to yield the desired amine derivative. A preferred class of biologically active substances used herein is the catecholamines.

REFERENCES:
patent: 3337628 (1967-08-01), Crowther et al.
patent: 3410901 (1968-11-01), Kunz et al.
patent: 3432545 (1969-03-01), Howe
patent: RE27822 (1973-11-01), Koppe et al.

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