Amino-, mercapto- and -oxy-substituted-phenyl and -phenalkyl imi

Details Amino-, mercapto- and -oxy-substituted-phenyl and -phenalkyl imi Amino-, mercapto- and -oxy-substituted-phenyl and -phenalkyl imi

1975-04-11

1977-02-01

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

2602955S, 260309, C07D23360, C07D23356

Patent

active

040062430

ABSTRACT:
Compounds of the formula ##STR1## wherein Z is a direct bond or alkylene of 1 - 3 carbon atoms which is unsubstituted or substituted on the carbon atom alpha to the phenyl group by alkyl or unsubstituted or substituted phenyl, R.sub.2 and R.sub.3 singly are H, alkyl, alkoxy, alkylmercapto, halo, nitro or, collectively, C.sub.4 H.sub.4, and R.sub.4 is alkenyl, alkinyl, unsubstituted or substituted phenyl or phenylalkyl, or, when Z is substituted methylene, also alkyl, are useful in combating Germatophyte infections, especially Trichophyton rubrum and mentagrophytes, and yeast infections, especially Candida albicans, as well as bacterial and fungal infections.

REFERENCES:
patent: 3711487 (1973-01-01), Draber et al.
patent: 3769422 (1973-10-01), Timmler et al.
patent: 3833603 (1974-09-01), Buchel et al.
patent: 3927017 (1975-12-01), Heeres et al.
Cannon et al., Chem. Abst. 1958, vol. 52, Cols. 8124-8125.

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