Amino derivatives of 4"-deoxy-oleandomycin

Details Amino derivatives of 4"-deoxy-oleandomycin Amino derivatives of 4"-deoxy-oleandomycin

1978-01-17

1979-02-20

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 17, C07H 1708, A01N 900

Patent

active

041408489

ABSTRACT:
Derivatives of oleandomycin, its 11-monoalkanoyl and 11,2'-dialkanoyl esters having at the 4"-position an amino group substituted with a group having the formula --(CH.sub.2).sub.n --Z--R wherein n is an integer from 2 to 4 when Z is O, S, SO, SO.sub.2 or NH, and n is an integer from 1 to 4 when Z is CO or CHOH, and R is a phenyl, substituted phenyl or a heterocyclyl group, their preparation, and use as antibacterial agents is described.

REFERENCES:
patent: 3963696 (1976-06-01), Martin et al.
patent: 4036853 (1977-07-01), Sciavolino

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