Amino D-manno-2-octulopyranosidonate containing compounds, pharm

Details Amino D-manno-2-octulopyranosidonate containing compounds, pharm Amino D-manno-2-octulopyranosidonate containing compounds, pharm

1985-08-19

1986-09-23

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 11, 536 187, 536 53, 536 55, A61K 3170, C07H 506

Patent

active

046135901

ABSTRACT:
Aminodeoxy derivatives of 3-deoxy-D-manno-2-octulosonic acid (KDO) are potent inhibitors of bacterial enzymes and a novel class of antibacterial agents.

REFERENCES:
patent: 3255174 (1966-06-01), Bannister
patent: 4228274 (1980-10-01), Ponpipom et al.
patent: 4273766 (1981-06-01), Stanek
Charon, et al., "J.C.S." Perkin I pp. 1971-1977, 1980.
Collins, et al., "J.C.S. Chem. Comm." pp. 1139-1140, 1981.
Strain, et al., "J. Bio. Chem.", vol. 258, No. 22, pp. 13466-13477, 1983.
Strain, et al., "J. Bio. Chem.", vol. 258, No. 5, pp. 2906-2910, 1983.
Bigham, et al., "J. Med. Chem.", vol. 27, pp. 717-726, 1984.
Molin et al., "Tetrahedron Letters," vol. 26, No. 5, pp. 677-680, 1985.

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