Amino-benzofuryl-and thienyl-derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514470, 549466, 549468, 5462817, 548248, A61K 3134, C07D30780

Patent

active

056229895

ABSTRACT:
6-Amino-benzofuryl- and thienyl-derivatives can be prepared by reacting appropriate amino-substituted benzoyl phenols with appropriate substituted acetophenones and subsequent modification of the substituents. The compounds are useful for the treatment of actual and chronic inflammatory diseases, particularly of the airways and the gastro-intestinal tract.

REFERENCES:
patent: 5120742 (1992-06-01), Rasmusson et al.
Kunchell et al., Chem. Ber., vol. 36, p. 1260-1262 (1903).
Sarhan, Egyptian, J. Pharm. Sci, vol. 33 (3-4), pp. 631-638 1992.
Chemical Abstracts, vol. 77, No. 23, abstract No. 151884g, (1972).
Chemical Abstracts, vol. 78, No. 25, abstract No. 159427b, (1973).
S. Nagata et al., Int. Arch. Allergy Immonol., vol. 97, pp. 194-199, (1992) .

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