Amino and substituted amino phosphinylalkanoyl compounds

Details Amino and substituted amino phosphinylalkanoyl compounds Amino and substituted amino phosphinylalkanoyl compounds

1982-11-01

1983-11-22

Raymond, Richard

Chemistry of carbon compounds

Dipeptides, e.g., aspartame, anserine, carnosine, etc.

260941, 546 22, 546 24, 548413, 549 6, 549218, C07F 932, C07F 958, C07F 965

Patent

active

044168314

ABSTRACT:
Compounds of the formula ##STR1## wherein X is an imino acid or ester and R.sub.1 is hydrogen, ##STR2## are useful hypotensive agents due to their angiotensin converting enzyme inhibition activity.

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patent: 4154935 (1979-05-01), Ondetti et al.
patent: 4168267 (1979-09-01), Petrillo
patent: 4192878 (1980-03-01), Ondetti
patent: 4217359 (1980-08-01), Krapcho
patent: 4234489 (1980-11-01), Ondetti et al.
Mauger et al., "Analogs and Homologs of Proline and Hydroxyproline" Chem. Review, vol. 66, pp. 47-86 (1966).

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