Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2004-10-05
2008-08-26
Davis, Brian J (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C564S099000, C514S605000, C514S650000
Reexamination Certificate
active
07417169
ABSTRACT:
The present invention provides compounds represented by general formula (I):a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein R1is hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R4, R5and R6is independently hydrogen, halogen, lower alkyl or lower alkoxy; R7is hydrogen or lower alkyl; R8is hydrogen, halogen, lower alkyl, lower alkoxy, etc; R9is —COR10, -A1-COR10, —O-A2-COR10, etc; Ar is optionally substituted phenyl or heteroaryl; and A is a bond, —OCH2—, etc, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.
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patent: 2003/0212063 (2003-11-01), Lafontaine et al.
patent: WO 99/65877 (1999-12-01), None
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The American Heritage Dictionary of the Enlish Language 4thed., (2000), Houghton Mifflin Co., Boston MA, p. 1406.
Akahane Satoshi
Ishikawa Takehiro
Kobayashi Jun'ichi
Muranaka Hideyuki
Nakamura Tetsuya
Davis Brian J
Kissei Pharmaceutical Co. Ltd.
Sughrue & Mion, PLLC
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