Amino alcohol compounds or phosphonic acid derivatives thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07638551

ABSTRACT:
A method for the prevention or treatment of an immunology-related disease, which is not rheumatoid arthritis or psoriasis, in a mammal in need thereof which involves administering to the mammal a pharmaceutically effective amount of a compound, a pharmacologically acceptable salt of the compound or a pharmacologically acceptable ester of the compound, wherein the compound is a compound having a formula (Ia):wherein R1and R2are each a hydrogen, R3is hydrogen; R4is C1-C2alkyl; n is 2; X is ═N—D, wherein D is hydrogen C1-C4alkyl or phenyl; Y is ethylene, ethynylene, —CO—CH2or phenylene; Z is ethylene or trimethylene; R5is an unsubstituted C3-C10cycloalkyl, an unsubstituted C6-C10aryl, or a C3-C10cycloalkyl or a C6-C10aryl substituted with 1 to 3 substituents selected from the group consisting of halogen, lower alkyl, halogeno lower alkyl and lower alkoxy; and R6and R7are each hydrogen.

REFERENCES:
patent: 3726948 (1973-04-01), Botts
patent: 4363918 (1982-12-01), Albert et al.
patent: 4386090 (1983-05-01), Moinet et al.
patent: 4536601 (1985-08-01), Tukamoto et al.
patent: 4613596 (1986-09-01), Moroni
patent: 4634689 (1987-01-01), Witkowski et al.
patent: 4667038 (1987-05-01), Clark et al.
patent: 4716155 (1987-12-01), Karanewsky et al.
patent: 4792568 (1988-12-01), Auerbach
patent: 4888338 (1989-12-01), Godfroid et al.
patent: 4977171 (1990-12-01), Suzuki et al.
patent: 5002966 (1991-03-01), Skidmore et al.
patent: 5037853 (1991-08-01), Brooks et al.
patent: 5037958 (1991-08-01), Hashimoto et al.
patent: 5039706 (1991-08-01), Wilkerson
patent: 5061704 (1991-10-01), Wierzbicki et al.
patent: 5068247 (1991-11-01), Fujita et al.
patent: 5112848 (1992-05-01), Brooks et al.
patent: 5130487 (1992-07-01), Budai et al.
patent: 5135947 (1992-08-01), Robertson et al.
patent: 5177085 (1993-01-01), Naef
patent: 5219884 (1993-06-01), Fujita et al.
patent: 5234934 (1993-08-01), Budai et al.
patent: 5260329 (1993-11-01), Mongelli et al.
patent: 5266599 (1993-11-01), Aubard et al.
patent: 5276190 (1994-01-01), Boesten et al.
patent: 5288751 (1994-02-01), Brooks et al.
patent: 5433896 (1995-07-01), Kang et al.
patent: 5470878 (1995-11-01), Michnick et al.
patent: 5501980 (1996-03-01), Katerinopoulos et al.
patent: 5534539 (1996-07-01), Mongelli et al.
patent: 5573909 (1996-11-01), Singer et al.
patent: 5604229 (1997-02-01), Fujita et al.
patent: 5641783 (1997-06-01), Klein et al.
patent: 5686479 (1997-11-01), Okumoto et al.
patent: 5714605 (1998-02-01), Vazquez et al.
patent: 5719176 (1998-02-01), Fujita et al.
patent: 5723218 (1998-03-01), Haugland et al.
patent: 5837703 (1998-11-01), Kumar et al.
patent: 5891892 (1999-04-01), Cheng et al.
patent: 5922770 (1999-07-01), Peschke et al.
patent: 5948820 (1999-09-01), Fujita et al.
patent: 5952316 (1999-09-01), Fujita et al.
patent: 6004565 (1999-12-01), Chiba et al.
patent: 6013802 (2000-01-01), Hoyland et al.
patent: 6028098 (2000-02-01), Goodman et al.
patent: 6077954 (2000-06-01), Cook et al.
patent: 6121329 (2000-09-01), Fujii et al.
patent: 6187821 (2001-02-01), Fujita et al.
patent: 6214873 (2001-04-01), Adachi et al.
patent: 6277888 (2001-08-01), Sakai et al.
patent: 6284915 (2001-09-01), Hirase et al.
patent: 6372800 (2002-04-01), Fujita et al.
patent: 6437165 (2002-08-01), Mandala et al.
patent: 6444686 (2002-09-01), Ko et al.
patent: 6455528 (2002-09-01), Adachi et al.
patent: 6462092 (2002-10-01), Sikorski et al.
patent: 6468998 (2002-10-01), Kuroita et al.
patent: 6476004 (2002-11-01), Sakai et al.
patent: 6476075 (2002-11-01), Sikorski et al.
patent: 6525069 (2003-02-01), Ko et al.
patent: 6605744 (2003-08-01), Abel et al.
patent: 6630492 (2003-10-01), Bauer et al.
patent: 6630493 (2003-10-01), Lubisch et al.
patent: 6638950 (2003-10-01), Duncia et al.
patent: 6649611 (2003-11-01), Blumberg et al.
patent: 6667025 (2003-12-01), Chiba et al.
patent: 6677375 (2004-01-01), Sikorski et al.
patent: 6683099 (2004-01-01), Sikorski et al.
patent: 6686353 (2004-02-01), Shiota et al.
patent: 6723745 (2004-04-01), Nishi et al.
patent: 6765023 (2004-07-01), Sikorski et al.
patent: 6960692 (2005-11-01), Kohno et al.
patent: 6963012 (2005-11-01), Kohno et al.
patent: 6964976 (2005-11-01), Nishi et al.
patent: 7199150 (2007-04-01), Nishi et al.
patent: 2002/0052349 (2002-05-01), Krauss et al.
patent: 2002/0091105 (2002-07-01), Mandala et al.
patent: 2003/0216393 (2003-11-01), Buschmann et al.
patent: 2003/0220390 (2003-11-01), Buschmann et al.
patent: 2003/0236297 (2003-12-01), Nishi et al.
patent: 2004/0034063 (2004-02-01), Ko et al.
patent: 2004/0058894 (2004-03-01), Doherty et al.
patent: 2004/0082790 (2004-04-01), Duncia et al.
patent: 2004/0092603 (2004-05-01), Chiba et al.
patent: 2004/0097508 (2004-05-01), Lubisch et al.
patent: 2004/0132784 (2004-07-01), Nishi et al.
patent: 2004/0242654 (2004-12-01), Kohno et al.
patent: 2004/0254222 (2004-12-01), Kohno et al.
patent: 2007/0105933 (2007-05-01), Nishi et al.
patent: 2007/0149597 (2007-06-01), Nishi et al.
patent: 2007/0191468 (2007-08-01), Nishi et al.
patent: 0 125 315 (1984-11-01), None
patent: 0 167 459 (1986-01-01), None
patent: 0 297 782 (1989-01-01), None
patent: 0 300 688 (1989-01-01), None
patent: 0 480 659 (1992-04-01), None
patent: 0 492 497 (1992-07-01), None
patent: 0 520 336 (1992-12-01), None
patent: 0 627 406 (1994-12-01), None
patent: 0 778 263 (1997-06-01), None
patent: 1 002 792 (2000-05-01), None
patent: 1 050 301 (2000-11-01), None
patent: 1 176 140 (2002-01-01), None
patent: 1 201 236 (2002-05-01), None
patent: 1 319 651 (2003-06-01), None
patent: 1 431 275 (2004-06-01), None
patent: 1 431 284 (2004-06-01), None
patent: 1 134 687 (1968-11-01), None
patent: 2 022 085 (1979-12-01), None
patent: 2 054 588 (1981-02-01), None
patent: 58-105946 (1983-06-01), None
patent: 59-44345 (1984-03-01), None
patent: 62-123126 (1987-06-01), None
patent: 63-139179 (1988-06-01), None
patent: 1-104087 (1989-04-01), None
patent: 2-256612 (1990-10-01), None
patent: 3-246264 (1991-11-01), None
patent: 4-104796 (1992-04-01), None
patent: 5-294907 (1993-11-01), None
patent: 6-067229 (1994-03-01), None
patent: 6-345728 (1994-12-01), None
patent: 7-002665 (1995-01-01), None
patent: 7-138230 (1995-05-01), None
patent: 9-124564 (1997-05-01), None
patent: 10-81623 (1998-03-01), None
patent: 11-80026 (1999-03-01), None
patent: 11-310556 (1999-11-01), None
patent: 11-343300 (1999-12-01), None
patent: 2002-053575 (2002-02-01), None
patent: 2002-316985 (2002-10-01), None
patent: 2003-267974 (2003-09-01), None
patent: 2005-41867 (2005-02-01), None
patent: WO 93/09185 (1993-05-01), None
patent: WO 94/08943 (1994-04-01), None
patent: WO 96/06068 (1996-02-01), None
patent: WO 98/15278 (1998-04-01), None
patent: WO 98/22100 (1998-05-01), None
patent: WO 98/45249 (1998-10-01), None
patent: WO 00/27798 (2000-05-01), None
patent: WO 00/33836 (2000-06-01), None
patent: WO 00/53569 (2000-09-01), None
patent: WO 01/01978 (2001-01-01), None
patent: WO 01/08685 (2001-02-01), None
patent: WO 01/49663 (2001-07-01), None
patent: WO 01/49685 (2001-07-01), None
patent: WO 02/06268 (2002-01-01), None
patent: WO 02/18395 (2002-03-01), None
patent: WO 02/067915 (2002-09-01), None
patent: WO 02/076995 (2002-10-01), None
patent: WO 02/094342 (2002-11-01), None
patent: WO 03/009836 (2003-02-01), None
patent: WO 03/013509 (2003-02-01), None
patent: WO 03/029205 (2003-04-01), None
patent: WO 03/035068 (2003-05-01), None
patent: WO 03/044015 (2003-05-01), None
patent: WO 03/097028 (2003-11-01), None
patent: WO 2004/024673 (2004-03-01), None
patent: WO 2004/028521 (2004-04-01), None
Huang, et al.,Kidney International, “Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice,” 51, pp. 94-103 (1997).
Berman et al.,J. Immunology, “Decreased Il-4 Production in New Onset Type 1 Insulin-Dependent Diabetes Mellitus1”. 157, pp. 4690-4696 (1996).
Cativiela et al., “Stereoselective synthesis of quaternary α-amino acids, Part 1: Acyclic compounds”,Tetrahedron: Asymmetry, 9, pp. 3517-3599 (1998).
Gander-Coquoz et al

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Amino alcohol compounds or phosphonic acid derivatives thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amino alcohol compounds or phosphonic acid derivatives thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amino alcohol compounds or phosphonic acid derivatives thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4107826

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.