Amino acyl cephalosporin derivatives

Details Amino acyl cephalosporin derivatives Amino acyl cephalosporin derivatives

1986-03-03

1988-11-08

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 514202, 530330, 530331, 540222, C07D50146, A61K 31545

Patent

active

047834439

ABSTRACT:
Antibacterial cephalosporin compounds of the Formula (I): ##STR1## wherein W is a pharmaceutically acceptable salt or a carboxyl-protecting group; n is an integer from 1 to 2; --X-- is --X.sup.1 -- where the X.sup.1 moieties are the same or different and selected from the group consisting of (D) or (L) ##STR2## Y is --O--; wherein R.sup.1 is selected from the group consisting of: ##STR3## R.sup.2 is H, --CH.sub.2 R.sup.4, --CHR.sup.5.sub.2 or --CR.sup.5.sub.3, wherein R.sup.4 is H, F, Cl, Br, --OH, --CN, ##STR4## --CH(CH.sub.3).sub.2, --CH.sub.2 (OH), ##STR5## or --C.tbd.CH, where Q.sup.1, Q.sup.2 and Q.sup.3 are the same or different and selected from the group consisting of H, F, Cl or Br; R.sup.5 is F, Cl or Br; and Z.sup.1 is H or an amino protecting group.

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