Amino acid preparation and therapy for treatment of stress and i

Details Amino acid preparation and therapy for treatment of stress and i Amino acid preparation and therapy for treatment of stress and i

1982-04-29

1984-03-20

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 31195

Patent

active

044381441

ABSTRACT:
Disclosed is a novel nutritional branched chain amino acid composition and its use for treatment of a patients suffering stress or injury, especially useful for parenteral or enteral alimentation of a patient suffering total or partial dysfunction or disuse of the gastrointestinal tract. The novel composition promotes and even optimizes patient wound healing, immune competence, host defense, and/or survival. The amino acids comprise from about 70 to 100% valine, isoleucine, and leucine, collectively, in a ratio of A:B:C, respectively, where A, B and C each independently has value from about 1 to 2. The novel composition is preferably used in the form of a parenteral infusion solution of from about 2 to 6%, most preferably 4% concentration.

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patent: 4252822 (1981-02-01), Berry
Surgery, Aug. 1976, vol. 80, No. 2, pp. 192-200.
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Hedden et al., Soc. for Exp. Biology & Medicine 410-415, (1979).
Berrotti et al., Surgical Forum, 27, 7-10, (1976).
Sakamoto et al., Surgical Forum, 30, 67-69, (1979).
Yoshimura et al., The Journ., of Parenteral & Ent. Nutrition, pp. 525-531.
The Health Quarterly (1979), p. 54.

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