Amino acid permease homolog

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 6, 435 912, 4353201, 435325, 435183, 435 691, 536 231, 536 232, 536 235, C12N 1500, C12N 900, C12N 1563, C12Q 168

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059423994

ABSTRACT:
The invention provides a human amino acid permease homolog (AAPH) and polynucleotides which identify and encode AAPH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of AAPH.

REFERENCES:
Gaugitsch, H.W. et al., "A Novel Transiently Expressed, Integral Membrane Protein Linked to Cell Activation", J. Biol. Chem., 267: 11267-11273 (1992).
Wolf, D.A. et al., "Expression of a Highly Conserved Oncofetal Gene, TA1/E16, in Human Colon Carcinoma and Other Primary Cancers: Homology to Schistosoma Mansoni Amino Acid Permease and Caenorhabditis Elegans Gene Products", Cancer Res., 56: 5012-5022 (1996).
Nagase, T. et al., "Prediction of the Coding Sequences of Unidentified Human Genes. VI The Coding Sequences of 80 New Genes (KIAA0201-KIAA0280) Deduced by Analysis of cDNA Clones from Cell Line KG-1 and Brain", DNA Res., 3:321-329 (1996).
Nomura, N., (Direct Submission), GenBank Sequence Database (Accession D87432), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 1665758; GI 1665759) (1997).
Kilberg, M.S. et al., "Characteristics and Hormonal Regulation of Amino Acid Transport System A in Isolated Rat Hepatocytes", Curr. Top. Cell Regul., 25: 133-163 (1985).

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