Amino acid modulated extended release dosage form

Details Amino acid modulated extended release dosage form Amino acid modulated extended release dosage form

2005-08-30

2005-08-30

Clardy, S. Mark (Department: 1616)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S464000, C424S465000, C424S468000, C424S469000, C424S475000, C424S482000, C424S484000, C424S485000, C424S486000, C424S488000, C424S489000, C424S490000, C424S499000, C424S500000, C424S501000, C514S769000, C514S972000, C514S772300, C514S773000, C514S777000, C514S778000, C514S780000, C514S781000, C514S782000, C514S784000, C514S788000, C514S960000, C514S961000, C514S964000, C514S965000

Reexamination Certificate

active

06936275

ABSTRACT:
Disclosed herein is a oral extended release dosage form comprising a plurality of granules of an effective amount of a pharmaceutically active compound, at least one amino acid, and an intragranular polymer in which the granule is dispersed within a hydrophilic extragranular polymer matrix which is more rapidly hydrating than the intragranular polymer. The amino acid is selected for hydropathy characteristics depending on solubility characteristics of the active compound.

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