Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide
Patent
1996-06-03
1998-10-13
Saunders, David
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using a micro-organism to make a protein or polypeptide
435 712, 435348, 435383, 435404, C12P 2100, C12N 500
Patent
active
058210890
ABSTRACT:
Incorporation of certain amino acid analogs into polypeptides produced by cells which do not ordinarily provide polypeptides containing such amino acid analogs is accomplished by subjecting the cells to growth media containing such amino acid analogs. The degree of incorporation can be regulated by adjusting the concentration of amino acid analogs in the media and/or by adjusting osmolality of the media. Such incorporation allows the chemical and physical characteristics of polypeptides to be altered and studied.
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Buechter Douglas D.
Connolly Kevin
Gruskin Elliott A.
Zhang Guanghui
Saunders David
Vander Vegt F. Pierre
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