Amino acid imide derivatives, usage thereof, and medicinal compo

Details Amino acid imide derivatives, usage thereof, and medicinal compo Amino acid imide derivatives, usage thereof, and medicinal compo

1988-12-22

1990-04-10

Gerstl, Robert

Textiles: spinning, twisting, and twining

548200, 548201, C07D41702, A61K 31425

Patent

active

049161466

ABSTRACT:
Novel N-substituted amino acid imide derivatives are disclosed. The compounds are represented by formula (I): ##STR1## wherein n represents an integer of 0 to 5, and X and Y, which may be the same or different, represent a methylene group or a sulfur atom, provided that not both X and Y are methylene groups at the same time. The compounds are useful as a medicine for treating or preventing cerebral circulation disorder, cerebral metabolism disorder, or memory disturbance.

REFERENCES:
Beilsteins Handbuch der Organischen Chemie, 4th Edition, vol. 27, part 6, pp. 3954-3955, 1984: Springer-Verlag, Berlin, D; p. 3954, formula VII; p. 3955, lines b-g.
Journal of Biochemistry, vol. 104, No. 4, 1988, pp. 580-586, Nagasaki, J. P.; D. Tsuru et al, "Thiazolidine Derivatives as Potent Inhibitors Specific for Prolyl Endopeptidase".

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