Amino acid hydroxyethylamino sulfonamide retroviral protease inh

Details Amino acid hydroxyethylamino sulfonamide retroviral protease inh Amino acid hydroxyethylamino sulfonamide retroviral protease inh

1998-03-03

1999-10-12

Stockton, Laura L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142278, 5142372, 548526, 548568, 548198, 548197, 548199, A61K 3140, C07D20706

Patent

active

059656018

ABSTRACT:
Selected amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.

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