Amino acid ester and amide renin inhibitor

Details Amino acid ester and amide renin inhibitor Amino acid ester and amide renin inhibitor

1984-12-14

1986-10-07

Phillips, Delbert R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549 76, 549 77, 549493, 548344, 548495, 564152, 564153, 564154, 564157, 564159, 560 24, 560 37, 560159, C07D21170, C07D33322, C07D30702, C07D23364, C07D20918, C07C10319, C07C10300, C07C10320, C07C10307, C07C12506, C07C10102, C07C12506

Patent

active

046160884

ABSTRACT:
Compounds of the formula ##STR1## wherein A is ##STR2## intervene in the conversion of angiotensinogen to angiotensin II by inhibiting renin and thus are useful as anti-hypertensive agents.

REFERENCES:
patent: 4470973 (1984-09-01), Natarajan et al.
patent: 4514391 (1985-04-01), Gordon et al.
The Peptides, vol. 1, Academic Press, N.Y. 1965, pp. XXVII-XXIX.

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