Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-01-23
1996-08-06
Dodson, Shelley A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514885, 560 41, 560169, 562450, 562561, 546146, 546147, 546174, 546175, 546267, 546335, 546336, 546337, 5483381, 548470, 548516, 564153, 564157, A61K 3144, C07D21132, C07D21346
Patent
active
055434231
ABSTRACT:
The present invention relates to compounds that can maintain, increase, or restore sensitivity of cells to therapeutic or prophylactic agents. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well-suited for treatment of multi-drug resistant cells, for prevention of the development of multi-drug resistance, and for use in multi-drug resistant cancer therapy.
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Harding Matthew W.
Zelle Robert E.
Dodson Shelley A.
Haley, Jr. James F.
Marks Andrew S.
McDonell Leslie A.
Vertex Pharmaceuticals Incorporated
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