Amino acid derivatives with angiotensin II antagonist properties

Details Amino acid derivatives with angiotensin II antagonist properties Amino acid derivatives with angiotensin II antagonist properties

1991-04-12

1991-09-03

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514252, 514326, 514397, 514400, 548336, 548337, 548341, 544139, 544370, 546210, C07D23368, C07D23364, A61K 31415

Patent

active

050455400

ABSTRACT:
This invention relates to novel amino acid derivatives which antagonize the binding of angiotensin II to its receptors. The compounds are useful in the treatment of hypertension, heart failure, glaucoma, and hyperaldosteronism. Methods of making the compounds, novel intermediates useful in the separation of the compounds, compositions containing the compounds and methods of using them are also covered.

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