Amino-acid derivatives, their preparation and their use as pharm

Details Amino-acid derivatives, their preparation and their use as pharm Amino-acid derivatives, their preparation and their use as pharm

1984-04-09

1985-10-08

Brust, Joseph Paul

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

514521, C07C12178, A61K 31275

Patent

active

045459428

ABSTRACT:
New compounds useful as immunoregulatory and antineoplastic agents are amino-acid derivatives of formula: ##STR1## wherein: n is an integer from 1 to 5;

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Knobler, et al., J. Chem. Soc., C., 14, pp. 1821-1824, (1969).
Wakamatsu, et al., J. Chem. Soc., D., Chem. Commun., 23, p. 1540, (1971).
Pichat, et al., Bull. Soc. Chim., Fr., (1970), 5, pp. 1837-1838.
Umezawa, et al., J. Antibiotics, 29(8), pp. 857-859, (1976).
Kobayashi, et al., Synthesis and Immunological Activities of Muramyl Dipeptide Derivatives, 7th Symposium on Progress in Organic Reactions and Synthesis; Gifu, Japan, (1980).
Wegman, et al., C.A., 95, 169043p, (1981).

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