Amino acid derivatives and their use as thrombin inhibitors

Details Amino acid derivatives and their use as thrombin inhibitors Amino acid derivatives and their use as thrombin inhibitors

2005-01-04

2005-01-04

Stockton, Laura L. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S063000, C514S423000, C548S406000, C548S523000, C548S526000, C548S537000

Reexamination Certificate

active

06838478

ABSTRACT:
There is provided compounds of formula I,wherein R1, R2, R3, Rx, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

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