Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-04-01
2008-04-01
Jaisle, Cecilia M. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S226000, C546S209000, C546S208000, C546S189000, C546S248000, C544S058100, C544S111000, C514S235500, C514S316000, C514S318000, C514S227800
Reexamination Certificate
active
10429793
ABSTRACT:
The present invention relates to the compounds of the formula (I) and salts thereof (all the symbols are the same meanings as described in the specification).The compounds of the formula (I) possess inhibitory activity of N-type calcium channel, so they are useful as drug for prevention and/or treatment of cerebral infarct, transient ischemic attack, encephalomyelopathy after cardiac operation, spinal angiopathy, hypertension with stress, neurosis, epilepsy, asthma and pollakiuria etc. or agent for the treatment of pain.
REFERENCES:
patent: 4780469 (1988-10-01), Toda et al.
patent: 4962225 (1990-10-01), Okada et al.
patent: 5596000 (1997-01-01), Esser et al.
patent: 5731340 (1998-03-01), Bras et al.
patent: 2003/0013725 (2003-01-01), Seko et al.
patent: 0 194 464 (1986-09-01), None
patent: 0 237 082 (1987-09-01), None
patent: 0 405 391 (1991-01-01), None
patent: 0 520 200 (1992-12-01), None
patent: 0 697 403 (1996-02-01), None
patent: 0 757 037 (1997-02-01), None
patent: 0 780 386 (1997-06-01), None
patent: 0 805 147 (1997-11-01), None
patent: 6-80696 (1994-03-01), None
patent: 8-208690 (1996-08-01), None
patent: 8-217671 (1996-08-01), None
patent: 8-217751 (1996-08-01), None
patent: WO 89/02431 (1989-03-01), None
patent: WO 91/01976 (1991-02-01), None
patent: WO 93/15047 (1993-08-01), None
patent: WO 94/07815 (1994-04-01), None
patent: WO 94/12181 (1994-06-01), None
patent: WO 96/11940 (1996-04-01), None
patent: WO 97/49679 (1997-12-01), None
patent: WO 98/54123 (1998-12-01), None
patent: WO 99/02146 (1999-01-01), None
patent: WO 99/25686 (1999-05-01), None
New Drug Evaluation, Regional Drug and Therapeutics Centre of the UK, Mar. 1999.
Wen, et al., PubMed abstract of Sheng Li Ke Xue Jin Zhan, Jan. 2005; 36(1): 23-8.
“Prevent” from Webster's Comprehensive Dictionary, 1996.
Bernstein, et al., abstract of Neuroscience, 1999, vol. 94, No. 4, pp. 1083-1095.
Shimosawa, et al., Hypertension, Dec. 2004, pp. 897-902.
Souillac, et al., Characterization of Delivery Systems, Differential Scanning Calorimetry, pp. 217-1 (in Encyclopedia of Controlled Drug Delivery, 1999, John Wiley & Sons, pp. 212-227).
Dr. D. Lipscombe, Brown Univ., Providence, R.I., <www.brown.edu/Administration/News—Bureau/2006-07/06-099.html>, downloaded Jul. 2, 2007.
Time, Apr. 2, 1979, “Better living through Biochemistry,” <http://www.time.com/time/printout/0,8816,916741,00.html>, downloaded Jul. 9, 2007.
Smith, et al., Pain, 96 (2002) 119-127.
Sreitwieser et al,Introduction to Organic Chemistry, 2ndEdn., 1981, pp. 935-937, ISBN 0-02-418050-5; Macmilan Publishing Co., New York.
CAS printout for Connell et al, Oct. 1993.
CAS printout for Ravi, et al, Apr. 1984.
CAS printout for Bodanszky, et al, Feb. 1972.
CAS printout for Aubry, et al, May 1987.
Shono, Tatauya, “A New Synthetic Meth of α-amino acid from α-methoxyurethanes,” Tetrahedron Letters, vol. 22, No. 25, pp. 2411-2412, 1981.
M. Ashraf Shalaby et al., “Thiopeptide Synthesis. α-Amino Thionoacid Derivatives of Nitrobenzotriazole as Thioacylating Agents,”J. Org. Chem., (1996) 61(25), 9045-9048.
Kosaku Noda et al.., “A facile method for preparation of t-butyloxycarbonylamino acidp-nitroanilides,”Int. J. Peptide Protein Res(1990) 36(2), 197-200.
Shi Pu-Tao et al., “Opiate Multiple Receptor Binding Activity of Enkephalin Analogs,” ACTA Biochemica and Biophysica Sinica (Jan. 1983), vol. 15, No. 1, 67-76, abstract.
Castelhano et al., “Synthesis, Chemistry, and Absolute Configuration of Novel Transglutaminase Inhibitors Containing a 3-Halo-4,5-dihydroisoxazole,”Bioorganic Chemistry(1988), 16(3), 335-40.
V.F. Pozdnev et al.., “Activation of carboxylic acids by pyrocarbonates. Synthesis of arylamides ofN-protected amino acids and small peptides using dialkylk pyrocarbonates as condensing reagents,”Int. J. Peptide Protein Res.(1994) 44(1), 36-48.
Václav {hacek over (C)}e{hacek over (r)}ovsky, et al., “Papain-Catalyzed Synthesis of 2-Naphthylamdes of N-Acylamino Acids and Dipeptides,”Collection Czech Chem. Comm.(1987), vol. 52, 2309-16.
F. Orosz et al., “Derivatives of DL-1,2,3,4-Tetrahydro-2-Naphthylamine Acylated with Amino Acids,” Acta Chimica Academiae Scientiarum Hungaricae (1966) 49(3), 291-302.
Michio Namikoshi et al., “Use of Tetrabutylammonium Fluoride as a Facile Deprotecting Reagent for 4-Nitrobenzyl, 2,2,2-Tricholorethyl, and Phenacyl Esters of Amino Acids,”J. Org. Chem(1991), 56, 5464-5466.
Tohru Sugawara et al , “Application of a Unique Automated Synthesis System for Solution-phase Peptide Synthesis,”Chem. Pharm. Bull.(1995), 43(8), 1272-1280.
Nobutaka Fujii et al., “Studies on Peptides. CXXXII. Evaluation of Two β- Carboxyl Protecting Groups of Aspartic Acid, Cycloheptyl and Cyclooctyl, for Peptide Synthesis,”Chem. Pharm. Bull(1985), 34(2), 864—8.
Haruaka Yajima et al Chem. Pharm. Bull., “Studies ofn Peptides. CXLIII. Evaluation of β-Menthylaspartate for Peptide Synthesis,” (1986), 34(10) 4356-61.
Tam et al., “Mechanisms of Aspartimide Formation: The effects of Protecting Groups, Acid, Base, Temperature and Time,”Peptide Research(1988), 1(1) 6-18.
Gasc et al., Chemical Abstracts, vol. 114:82543, 1991.
Shengeliya et al., Chemical Abstracts, vol. 107:77510, 1987.
Kowollik et al., Chemical Abstracts, vol. 103:105274, 1985.
Lau et al., Chemical Abstracts, vol. 99:64868, 1983.
Gillessen et al., Chemical Abstracts, vol. 72:67256, 1970.
Poroshin et al., Chemical Abstracts, vol. 63:89274, 1965.
Kato Masashi
Seko Takuya
Jaisle Cecilia M.
Ono Pharmaceutical Co. Ltd.
Sughrue & Mion, PLLC
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