Amino acid derivatives

Details Amino acid derivatives Amino acid derivatives

2005-03-08

2010-06-01

Shameem, Golam M (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S215000, C548S221000, C549S429000, C549S432000, C549S434000, C564S305000, C514S461000, C514S465000, C514S646000

Reexamination Certificate

active

07728020

ABSTRACT:
The present invention relates to new amino acid derivatives, process for the production, their use, in particular in transplantation, and pharmaceutical compositions containing them.

REFERENCES:
patent: 02/076995 (2002-10-01), None
patent: 03/099192 (2003-12-01), None
Winn et al., “Homologs of dopa, .alpha.-methyldopa, and dopamine as potential cardiovascular drugs”, Journal of Medicinal Chemistry, vol. 18, No. 4, pp. 434-437 (1975).
Lane et al., “A new method for the stereoselective synthesis of .alpha.-substituted serine amino acid analogues”, Organic Letters, vol. 5, No. 22, pp. 4017-4020 (2003).
Kiuchi et al., “Synthesis and immunosuppressive activity of 2-substituted 2-aminopropane-1,3-diols and 2-aminoethanols”, Journal of Medicinal Chemistry, vol. 43, No. 15, pp. 2946-2961 (2000).
Shtacher et al., “Iodophenyl derivatives of .alpha.-methyl alanine and isovaline as potential oral cholecystographic agents”, Journal of Medicinal Chemistry, vol. 15, No. 11, pp. 1174-1177 (1972).
Harding et al., “The preparation and alkylation of a butanedione-derived chiral glycine equivalent and its use for the synthesis of alpha-amino acids and alpha,alpha-disubstituted amino acids”, Tetrahedron, vol. 60, No. 35, pp. 7679-7692 (2004).

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