Amino acid derivatives

Details Amino acid derivatives Amino acid derivatives

1977-01-17

1978-09-12

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

041137159

ABSTRACT:
New substituted acyl derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.

REFERENCES:
H. Garras, et al., Journal of Med. 291, 1974, pp. 817-821.
S. Oparil, et al., Journal of Med. 291, 1974, pp. 389-401.
Schmidt, et al., Angew. Chem., Intl. Ed. Engl. 15, 1976, p. 42.
Latruffe et al., "Biochimie", 57, (1975), 849-857.
Fu-Chih Huang et al., "J.A.C.S.", 97, (1975), 3858-3859.
P. Adriaens et al., Antimicrobial Agents and Chemotherapy, vol. 8, (1975), 638-635.
George Pettit, "Synthetic Peptides", vol. 1, (1971), pp. 94-104.

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