Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-25
1997-09-23
Spivack, Phyllis G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546125, 546129, A61K 3144, C07D45106, C07D45110, C07D45112
Patent
active
056705158
ABSTRACT:
N-Acyl-.alpha.-aminocarboxylic acid derivatives of the formula ##STR1## wherein L, R' to R'" and Q have the definitions given in the specification, are for the treatment or prophylaxis of illnesses which are caused by the binding of adhesive proteins to blood platelets, by blood platelet aggregation and cell-cell adhesion. They are manufactured by cleaving off protecting groups in corresponding protected compounds or by converting the cyano group into the amidino group in corresponding nitriles.
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Alig Leo
Hadvary Paul
Hurzeler Marianne
Muller Marcel
Steiner Beat
Ciambrone Coletti Ellen
Hoffmann-La Roche Inc.
Johnston George W.
Spivack Phyllis G.
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