Amino acid chelated compositions for delivery to specific biolog

Details Amino acid chelated compositions for delivery to specific biolog Amino acid chelated compositions for delivery to specific biolog

1986-02-06

1989-09-05

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 514 19, 514 21, 514494, 514880, 514891, 514893, 514492, 514499, 514500, 514501, 514502, 514505, 514419, 514428, 514399, A61K 3702, A61K 31555, A61K 3128, A61K 31315

Patent

active

048638986

ABSTRACT:
Amino acid chelates having a ligand to divalent metal mole ratio of at least 2:1 and having a molecular weight of not more than 1500 and preferably not more than 1000 and also having a stability constant of between about 10 and 10 are formulated for delivery to one or more specific tissue sites within a mammal. The ligand utilized in formulating the amino acid chelate is a naturally occuring amino acid or a dipeptide, tripeptide or quadrapeptide thereof. The selection of an appropriate ligand with which to form the chelate provides a product that, when entering the bloodstream of the mammal, either by mean of oral ingestion or injection, has a propensity to migrate to one or more targeted tissue sites within the mammal.

REFERENCES:
patent: 3887704 (1975-06-01), Lichtenstein
patent: 4020158 (1977-04-01), Ashmead et al.
patent: 4167564 (1979-09-01), Jensen
patent: 4172072 (1979-10-01), Ashmead
patent: 4599152 (1986-07-01), Ashmead
Frost, Science Counselor, Jun. 1956.
Rabin, Trans Farady Society, 52, 1130-1136 (1956).
Perkins, Biochem. Journal, 57, 702-704 (1954).
Bossu, J. Am. Chem. Soc., 99, 2195-2203 (1977).
Martin, J. Am. Chem. Soc., 82, 495-498 (1960).

Affiliated with

Also associated with

Rating

Amino acid chelated compositions for delivery to specific biolog does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amino acid chelated compositions for delivery to specific biolog, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amino acid chelated compositions for delivery to specific biolog will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-243473