Amines substituted with a dihydro-benzofuranyl or with a dihydro

Details Amines substituted with a dihydro-benzofuranyl or with a dihydro Amines substituted with a dihydro-benzofuranyl or with a dihydro

1999-08-16

2000-07-25

Owens, Amelia

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549 60, 5462841, 544322, 548190, 5483114, C07D30778, C07D40900

Patent

active

060938382

ABSTRACT:
Compounds of Formula 1 and of Formula 2 ##STR1## where the symbols have the meaning defined in the specification, have retinoid-like biological activity.

REFERENCES:
patent: 5455265 (1995-10-01), Chandraratna
patent: 5616712 (1997-04-01), Teng et al.
patent: 5877207 (1999-03-01), Klein et al.
Dawson and William H. Okamura, Chemistry and Biology of Synthetic Retinoids, published by CRC Press, Inc., 1990, pp. 334-335.
Verma & Boutwell, Cancer Research, (1977), 37, 2196-2201.
Cancer Research: 1662-1670 (1975).
Feigner P. L. and Holm M. (1989) Focus, 112.
Heyman et al., Cell 68, 397-406 (1992).
Allegretto et al., J. Biol. Chem. 268, 26625-26633.
Mangelsdorf et al., The Retinoids: Biology, Chemistry and Medicine, pp. 319-349, Raven Press Ltd., New York.
Cheng et al., Biochemical Pharmacology vol. 22 pp. 3099-3108.
Klein et al., J. Biol. Chem. 271, 22692-22696 (1996).
Chen et al. (1987) Mol. Cell. Biol. 7, 2745-2752.
de Wet (1987) Mol. Cell. Biol. 7, 725-737.
Nagpal et al., Embo J. 12, 2349-2360 (1993).
Corey, E. J. Schmidt, G., Tet. Lett., 399 (1979).
Omura, K., Swern, D., Tetrahedron, 1978, 34, 1651.
Bennett et al. in J. Chem. Soc., 1936, 1114.
J. Med. Chem., 1998, 41, 1124-1137.

Affiliated with

Also associated with

Rating

Amines substituted with a dihydro-benzofuranyl or with a dihydro does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amines substituted with a dihydro-benzofuranyl or with a dihydro, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amines substituted with a dihydro-benzofuranyl or with a dihydro will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1337605