Aminediols for the treatment of Alzheimer's disease

Details Aminediols for the treatment of Alzheimer's disease Aminediols for the treatment of Alzheimer's disease

2006-05-30

2006-05-30

McKane, Joseph K. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S211010, C514S218000, C514S247000, C514S423000, C514S431000, C514S432000, C514S448000, C514S450000, C514S451000, C514S471000, C544S002000, C544S063000, C544S162000, C544S335000, C546S304000, C546S314000, C548S190000, C548S200000, C549S010000, C549S074000, C549S346000, C549S425000, C549S483000

Reexamination Certificate

active

07053109

ABSTRACT:
The present invention relates to compounds of formula (I):useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.

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