Amine stabilized aminoglycoside formulations

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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436546, 436826, 536 136, 536 137, 536 168, G01N 3353, C07H 1520, C07G 1100

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active

048163910

ABSTRACT:
Novel formulations are provided containing conjugated or unconjugated aminoglycosides, particularly labeled glycosides, a small amount of a polyamine, and additional additives, such as buffer, salt, and inert protein. The level of immunologic activity of the aminoglycoside is retained for long periods of time when stored in glass containers.

REFERENCES:
patent: 4100268 (1978-07-01), Scherr
patent: 4218335 (1980-08-01), Mochida et al.
Hyde et al., Endocrinology (111:4), 1421-1423, 1982.
Naor et al., Molecular and Cellular Endocrinology (25), 85-97, 1982.
Chang et al., Biochemical and Biophysical Research Communications, (134:1), 134-139, 1986.

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