Amine intermediates for analgesic compounds

Details Amine intermediates for analgesic compounds Amine intermediates for analgesic compounds

1984-02-14

1985-04-02

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

2603303, 2603309, 546 15, 549 4, 549 13, 549 28, 549 74, 549214, 549331, C07D30794

Patent

active

045089116

ABSTRACT:
1,2-Cycloaliphatic diamines and protected diamines of the formulas II and IIa ##STR1## and ##STR2## wherein the wavy line bonds, p, n, R, R.sub.1, R.sub.2, Z, m and Q are as defined in the specification, e.g., (.+-.)-(5.xi.,6.alpha.,7.beta.)-1-[6-methylamino-1-oxaspiro[4.5]dec-7-yl]p yrrolidine, are disclosed and claimed herein. These diamines and protected diamines are useful as intermediates for preparing mono-oxa, and thiaspirocyclic-benzene acetamide and benzamide analgesic compounds.

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