Amine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S259310, C514S246000, C544S256000, C544S280000, C544S180000, C544S194000

Reexamination Certificate

active

07816365

ABSTRACT:
Disclosed are compounds of formula (I),which are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and which can be employed, inter alia, for the treatment of tumours.

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Vippagunta et al., Advanced Drug Delivery Reviews 48: 3-26, 2001.
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Okabe, et al.: “Di Alkyl Bi Cyclic Hetero Cycles With a Bridgehead Nitrogen as Purine Analogs Possessing Significant Cardiac Inotropic Activity” Journal of Heterocyclic Chemistry, Bd. 20, Nr. 3, 1983, pp. 735-751, XP002322759; ISSN: 0022-152X.

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