Amine compounds and use thereof

Details Amine compounds and use thereof Amine compounds and use thereof

2007-02-13

2007-02-13

Shameem, Golam M. M. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S312700

Reexamination Certificate

active

10516158

ABSTRACT:
Novel amine compounds which are efficacious against diseases such as infection with HIV virus, rheumatism, and cancer metastasis include compounds represented by the following general formula (1), a pharmacologically acceptable salt thereof, or a prodrug thereof:wherein each of n1, n2, and n3is an integer of 1; each of R1, R2, R3, R4, R5, and R6is independently a hydrogen atom; A1is imidazole; A2is imidazole or imidazole substituted with an alkyl group; W is a phenyl group or naphthyl group; X is CH2; D is a group represented by -Q-Y—B, wherein Q is NR12and R12is a hydrogen atom or an alkyl group; Y is (CH2)m3and m3is an integer of 2 to 4; and B is N(R25R26), wherein each of R25and R26are independently a hydrogen atom, a C1–C6alkyl group or a C3–C6cycloalkyl group.

REFERENCES:
patent: 5086069 (1992-02-01), Klein et al.
patent: 5633231 (1997-05-01), Habich et al.
patent: 5886044 (1999-03-01), Widdowson et al.
patent: 6096773 (2000-08-01), Scott et al.
patent: 6750348 (2004-06-01), Bridger et al.
patent: 7091217 (2006-08-01), Bridger et al.
patent: 2004/0092556 (2004-05-01), Yamazaki et al.
patent: 2004/0157818 (2004-08-01), Yanaka et al.
patent: 2004/0254221 (2004-12-01), Yamazaki et al.
patent: 0 183 271 (1986-06-01), None
patent: 0 628 551 (1994-12-01), None
patent: 0 646 598 (1995-04-01), None
patent: 1 389 460 (2004-02-01), None
patent: 7-89988 (1995-04-01), None
patent: WO 98/06397 (1998-02-01), None
patent: WO 99/33787 (1999-07-01), None
patent: WO 2000/006086 (2000-02-01), None
patent: WO 2000/056729 (2000-09-01), None
patent: WO 01/10842 (2001-02-01), None
patent: WO 01/79168 (2001-10-01), None
patent: WO 2002/022600 (2002-03-01), None
patent: WO 02/094261 (2002-05-01), None
patent: WO 03/029218 (2003-04-01), None
patent: WO 2005/085209 (2005-10-01), None
Molino, M. et al., “CXCR4 on human endothelial cells can serve as both a mediator of biological responses and as a receptor for HIV-2,” Biochimica et Biophysica Acta (BBA), Molecular Basis of Disease, vol. 1500, Issue 2, Feb. 21, 2000, p. 227-240.
U.S. Appl. No. 10/591,722, filed Sep. 5, 2006, Atsushi Saitou et al.

Affiliated with

Also associated with

Rating

Amine compounds and use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amine compounds and use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amine compounds and use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3886065