Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1990-04-27
1992-08-25
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
564374, A61K 31135, C07C21552
Patent
active
051419629
ABSTRACT:
A compound selected from the group consisting of N-pentyl-N-phenethyl-3-hydroxyphenethylamine of the formula ##STR1## and its non-toxic, pharmaceutically acceptable acid addition salts having a remarkably dissociated antagonist affinity for kappa opiate receptor.
REFERENCES:
patent: 4130658 (1978-12-01), Nedelec et al.
patent: 4175136 (1979-11-01), Nedelec et al.
Nedelec et al, "Synthesis and Study of the Dopaminergic Activity of Di(Phenylethyl)amine Derivatives", Calif. 90 168185w (1979).
Cosquer Philippe
Delevallee Francoise
Droux Serge
Fortin Michel
Petit Francis
Raymond Richard L.
Roussel Uclaf
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