Amidoalkylation reactions of anilines

Details Amidoalkylation reactions of anilines Amidoalkylation reactions of anilines

1983-09-12

1985-10-08

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602393T, 2602444, A61K 3155, C07D47104, C07D48704

Patent

active

045459355

ABSTRACT:
Benzodiazepines having associated carbonyl lactam ring structure are synthesized from N-2-bromoethyl-5-alkoxy-2-pyrrolidinone and analine compounds, in the first ever such direct single step synthesis. The produced compounds are known biological active compounds having anti-anxiety activity similar to Valium.

REFERENCES:
patent: 3374264 (1968-03-01), Liskokovic et al.
patent: 3384635 (1968-05-01), Carabateas
patent: 3419569 (1968-12-01), Renner
patent: 3481921 (1969-12-01), Field et al.
patent: 3573322 (1971-03-01), Hester
patent: 3651083 (1972-03-01), Hester
patent: 3652588 (1972-03-01), Hester
patent: 3732212 (1973-05-01), Carabateas
patent: 3734919 (1973-05-01), Hester
patent: 3763183 (1973-10-01), Carabateas
patent: 3824230 (1974-07-01), Hester
patent: 3828039 (1974-08-01), Nakanishi et al.
patent: 3833591 (1974-09-01), McManus
patent: 3839357 (1974-10-01), Hester
patent: 3846443 (1974-11-01), Moffett
patent: 3867374 (1975-02-01), Reynolds et al.
patent: 3910946 (1975-10-01), Gall
patent: 3914250 (1975-10-01), Kim
patent: 3933794 (1976-01-01), Hester et al.
patent: 3980797 (1976-09-01), Jonas et al.
patent: 3984562 (1976-10-01), Wright
patent: 3998842 (1976-12-01), White et al.
patent: 4169150 (1979-09-01), Hara et al.
patent: 4186199 (1980-01-01), Glamkowski et al.
patent: 4264499 (1981-04-01), Hirai et al.
patent: 4362666 (1982-12-01), Wasley
Seto et al. Chem. Abstracts, vol. 89, Abstract No. 146944v, (1978).
Kraus, Chem. Abstracts, vol. 95, Abstract No. 7550z, (1981).
Hoover et al., Journal of Organic Chemistry, vol. 28, pp. 1825-1830, (1963).

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