Amidinourea derivative veterinary compositions for suppression o

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424246, 424249, 424250, 424251, 424256, 424263, 424267, 424269, 424270, 424272, 424273R, 424273P, 424274, 424303, 424304, 424311, 424317, 424320, 42424854, A61K 3117

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043406092

ABSTRACT:
Therapeutic compositions containing an amidinourea are used in the treatment of animals infested with blood residing parasites, particularly parasitic protozoal infestations of the blood and blood-forming organs.

REFERENCES:
patent: 3539616 (1970-11-01), Walls
patent: 3984467 (1976-10-01), Diana
patent: 4163022 (1979-07-01), Diamond
Curd, F. H. S. et al., "Synthetic Antimalarials, Part XLII, The Preparation of Guanylureas and Biurets corresponding to "Paludrine" and related Biguanides", J. Chem. Soc., p. 1732 (1949).
Skowronska-Serafin, B. and Urbanski, T., "Preparation of Derivatives of Amidineurea and their Reactions", Tetrahedron, vol. 10, pp. 12-24 (1960).
Goodford, Walls et al., "Predictions of the antimalarial activity of arylamidinoureas", Br. J. Pharmac., vol. 48, pp. 650-654 (1973).
Douglas et al., Arzneimittel Forschung (Drug Research), 28(II), pp. 1433-1480 (1978).

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