Amidinosulphonic acid derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424270, 424272, 424269, 546275, 546276, 546277, 546280, 546290, 546311, 546331, 548136, 548203, 548214, 548215, 548247, 548262, C07D21332, A61K 3144

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042658969

ABSTRACT:
Amidinosulphonic acid derivatives carrying an unsaturated nitrogen heterocycle-containing substituent, representative of which are N-methyl-N'[2-(5-methyl-4-imidazolylmethylthio)-ethyl] amidinosulphonic acid and N-methyl-N'-[2-(3-chloropyrid-2-ylmethylthio) ethyl] amidinosulphonic acid, are histamine H.sub.2 -receptor antagonists.

REFERENCES:
patent: 3734924 (1973-05-01), Dennis
patent: 3736331 (1973-05-01), Black et al.
patent: 4090026 (1978-05-01), Durant et al.
patent: 4109003 (1978-08-01), Durant et al.
patent: 4118502 (1978-10-01), Durant et al.
patent: 4154838 (1979-05-01), Durant et al.
patent: 4210658 (1980-07-01), Durant et al.
Official Gazette, Aug. 19, 1980, pp. 1027, 1036, 1058.

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