Amidinophenylalanine derivatives, a process for their preparatio

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514 54, 514319, 514330, 514456, 514604, 514622, 546205, 546206, 546226, 564 85, 564 89, 564 92, 549399, 549400, 549401, A61K 3118

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active

055718442

ABSTRACT:
The invention relates to amidinophenylalanine derivatives, to the synthesis of these compounds, to their use and to pharmaceutical compositions which contain these compounds which act as thrombin inhibitors.

REFERENCES:
patent: 4093712 (1978-06-01), Okamoto et al.
patent: 4791102 (1988-12-01), Bernat et al.
patent: 5274098 (1993-12-01), Stuer et al.
Eur. Polym. J. vol. 19, No. 12, pp. 1177-1183 (1983).
Yi-An Lu et al., "Pegylated Peptides I: Solid-Phase Synthesis of N a-Pegylated Peptides Using Fmoc Strategy," Peptide Research, 6:3(1993).

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