Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and

Details Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and

1997-07-07

2000-05-02

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514343, 514344, 514345, 514347, 514348, 514349, 514350, 514351, 514352, 514354, 514356, 514378, 514380, 514422, 514423, 514424, 514426, 514427, 514428, 514444, 514445, 514447, 514448, 514451, 514459, 514460, 514461, 514471, 514472, 514473, 5462721, 5462764, 5462784, 5462787, 5462791, 548240, 548243, 548244, 548517, 548518, 548519, 548521, 548530, 548531, 548532, 548541, 548546, 548547, 548548, 548550, 548556, 548557, 548560, 548561, 548562, 548565, 548566, 548568, 548570, 548571, 548572, 548577, 549 59, 549

Patent

active

060573422

ABSTRACT:
The present application describes amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein one of D and D' may be C(.dbd.NH)NH.sub.2 and the other H, and J.sup.1 and J.sup.2 may be O or CH.sub.2, which are useful as inhibitors of factor Xa.

REFERENCES:
patent: 5418233 (1995-05-01), Linz et al.
patent: 5463071 (1995-10-01), Himmelsbach et al.

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