Amidinonaphthyl furancarboxylate derivatives and acid addition s

Details Amidinonaphthyl furancarboxylate derivatives and acid addition s Amidinonaphthyl furancarboxylate derivatives and acid addition s

1994-03-22

1996-07-02

Trinh, Ba Kim

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514471, 549229, 549484, 549492, 549493, 549494, 549495, A61K 31335, A61K 3134, C07D30746, C07D31714

Patent

active

055322670

ABSTRACT:
Amidinonaphthyl furancarboxylate derivatives of the formula I ##STR1## wherein A is a single bond or A denotes (a) a phenyl group, cyclopentyl group, or cyclohexyl group,
(b) an alkenylphenyl group, alkylphenyl group, phenylalkenyl group, or phenylalkyl group wherein alkyl is C.sub.1 to C.sub.7 alkyl and alkenyl is C.sub.2 to C.sub.7 alkenyl,
(c) a C.sub.1 to C.sub.18 alkyl or C.sub.2 to C.sub.7 alkenyl group which may be substituted by one or two substituents selected from C.sub.1 to C.sub.5 alkyl groups and quanidino groups, wherein an alkyl substituent together with the carbon atom to which it is attached may form a cycloalkyl ring having from 3 to 6 carbon atoms, or said C.sub.1 to C.sub.5 alkyl may itself be substituted by a C.sub.3 to C.sub.6 cycloalkyl ring, or
(d) --(CH.sub.2).sub.n --NH--CO--(CH.sub.2).sub.n' wherein n and n' may be the same or different and represent an integer from 1 to 4; and
wherein R denotes
(e) a hydroxyl group,
(f) a C.sub.1 to C.sub.7 alkoxy group which may be mono- or disubstituted by C.sub.1 to C.sub.5 alkyl,
(g) a phenyl-C.sub.1 -C.sub.4 alkoxy group,
(h) --OAl(OH).sub.2,
(i) an amino group,
(j) ##STR2## or (k) ##STR3## and pharmaceutically acceptable acid addition salts thereof, useful as pharmaceuticals.

REFERENCES:
patent: 4563527 (1986-01-01), Fujii et al.
patent: 4634783 (1987-01-01), Fujii et al.

Affiliated with

Also associated with

Rating

Amidinonaphthyl furancarboxylate derivatives and acid addition s does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amidinonaphthyl furancarboxylate derivatives and acid addition s, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amidinonaphthyl furancarboxylate derivatives and acid addition s will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1506779