Amidino protease inhibitors

Details Amidino protease inhibitors Amidino protease inhibitors

1999-03-16

2000-10-17

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514518, 514603, 514604, 514605, 514617, 514618, 514619, 514620, 514629, 514637, 558 56, 558 58, 564 85, 564 86, 564164, 564185, 564220, 564244, 564246, A61K 31155, A61K 3118, C07C25714, C07C31146

Patent

active

061333158

ABSTRACT:
Amidino and benzamidino compounds, including compounds of the formula: ##STR1## wherein R.sup.1 -R.sup.4, R.sup.6 -R.sup.9, Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit a number of proteolytic enzymes are described. Also described are methods for preparing the compounds of Formula I.

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