Amidino protease inhibitors

Details Amidino protease inhibitors Amidino protease inhibitors

1996-12-27

2000-03-07

Gupta, Yogendra N.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514618, 514619, 514627, 514602, 514603, 514605, 514518, 558 44, 558 55, 558 56, 564 80, 564 95, 564161, 564162, 564164, 564165, A61K 31185, A61K 3118, C07C30924, C07C25708

Patent

active

060341270

ABSTRACT:
Amidino and benzamidino compounds, including compounds of the formula: ##STR1## wherein R.sup.1 -R.sup.4, R.sup.6 -R.sup.9, Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit a number of proteolytic enzymes are described. Also described are methods for preparing the compounds of Formula I.

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