Amidino derivatives and their use as thrombin inhibitors

Details Amidino derivatives and their use as thrombin inhibitors Amidino derivatives and their use as thrombin inhibitors

2007-07-10

2007-07-10

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S317000, C514S423000, C546S226000, C548S531000, C548S950000

Reexamination Certificate

active

10815954

ABSTRACT:
There is provided compounds of formula Iwherein R1, Rx, Y, Ry, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

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