Amidino derivatives and their use as thrombin inhibitors

Details Amidino derivatives and their use as thrombin inhibitors Amidino derivatives and their use as thrombin inhibitors

2006-07-11

2006-07-11

Barts, Samuel (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S535000, C514S604000, C514S506000, C514S562000, C514S255030, C514S317000, C514S330000, C514S331000, C544S398000, C544S399000, C544S400000, C544S402000, C546S021000, C546S229000, C546S230000, C546S231000, C560S013000

Reexamination Certificate

active

07074820

ABSTRACT:
There is provided compounds of formula I,wherein R1, R2, R3, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

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